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doi: 10.1186/s12943-019-1089-9 13 XueZRXinYYJinWL

Furthermore, glutathione supports healthy mitochondria and protects long-term cardiovascular and neurological cellular integrity

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The future lies in developing allosteric modulators or subunit-selective antagonists (particularly for GluN2B-containing receptors) that can precisely modulate pathological hyperactivity in the auditory pathway without disrupting essential NMDA receptor functions elsewhere in the brain, thereby offering a more effective and tolerable treatment strategy for tinnitus (Rafe et al., 2024